Devices like computers, laptops, notebooks, etc. have become a common necessity in recent times. All such devices are incomplete with an efficiently working mouse. Using a comfortable mouse boosts your productivity when working on a computer. In the present article, the discussion is centered on the best vertical mice. They are ergonomically designed to prevent stress on your wrists and hands. When using an uncomfortable mouse for long hours, the small muscles and tendons in these body organs experience pain. The solution to this problem is to invest in the vertical mouses.
The ergonomic design of the vertical mice relieves the pain and numbness when working at your computer for long hours. These products are getting increasingly popular at homes and workplaces. This is because they are designed to keep your hands, wrists, and forearms in a natural position. Those who are suffering from carpal tunnel syndrome need not wear braces if they use a vertical mouse. Now you can boost your productivity when working on a computer with the choice of any of these best vertical mice:
Contents
List of 10 Best Vertical Mouses Review in 2025:
10. AmazonBasics Vertical Ergonomic 2.4G Wireless Optical Mouse:
When looking for a wireless vertical mouse, this optical mouse from AmazonBasics is a good choice. It comes equipped with 2.4 GHz wireless connectivity. Generally, it can work on all surfaces, even on glass. Both for short or prolonged use, this wireless optical mouse does not feel uncomfortable.
Prepared in ergonomic design, this mouse offers excellent comfort in hands, arms, and wrists. There are no hassles when it comes to compatibility. You can use it with most Windows and Mac operating systems. The build quality is durable and all the features are solid. Furthermore, the buttons work flawlessly.
Pros:
- Perfect for small and medium-sized hands
- Matte finish for improved grip
- Powerful wireless connectivity
Why We Liked It?
We liked the exceptional comfort and ergonomic design of this vertical mouse. It feels lightweight enough to carry to different places.
9. iClever Vertical Mouses – Wireless 6 Buttons:
Those who like to employ precise control on their mouse movements, this iClever vertical mouse is a good option. For long hours of computer work, this wireless mouse is the best companion. It comes equipped with an optical sensor with 2400 DPI. This aspect makes sure this ergonomic mouse flawlessly tracks the finest of movements easily.
Now you can get rid of hand aching when working in front of the computer for hours. It represents an excellent blend of style and comfort. Designed with professionals in mind, this mouse comes with precision shaping. So, it relieves pains and cramps in wrists. The side grips and thumb rest are included.
Pros:
- Ergonomic design for ultimate comfort
- Whisper quiet click
- An easy web browsing experience
Why We Liked Vertical Mouses?
Get your project done quicker with this wireless mouse. All the buttons are strategically placed for ease of use.
8. Nulaxy 2.4G Wireless Vertical Ergonomic Mouses:
An ergonomic mouse is a useful product for working professionals, gamers, and graphic designers. This Nulaxy mouse is ergonomically designed to protect your wrist against orthopedic injuries. Moreover, it can relieve pain if you are facing pain in the wrist. There is the availability of 6 buttons for use with a computer, laptop, desktop, PC, and Macbook. The thumb buttons are positioned comfortably. Each button is in easy reach.
The unique specialty is it comes with an adjustable DPI setting. This DPI switch enables you to switch between different DPI settings. So, the rubbery matte finish offers a premium feel quite better than a standard mouse.
Pros:
- 6 multi-functional buttons included
- Precise movement
- Beautiful matte finish for grip
Why We Liked It?
We liked the beautiful elegant matte finish that offers a nice grip. All the movements are flawless and precise.
7. Evoluent VerticalMouse 4 VM4RW Right Wireless:
The VM4RW mouse is an ergonomic vertical mouse from Evoluent. It gently supports your right hand in an erect neutral position. Due to the patented shape, this mouse prevents your hands against twisting your forearm. It is easy to program your mouse as per your needs. Moreover, it is easy to install on your computer system.
There is the freedom to change the mouse speed from low setting to high setting. The optical sensor controls are available on the side. So, you can use this device with all computers supporting Windows, Mac, and Linux OS.
Pros:
- Easy to program your mouse to your needs
- Broad compatibility
- Allows mouse speed adjustment
Why We Liked It?
The wide range of compatibility makes it a unique wireless mouse. So, there is no requirement to release the grip for adjusting speed.
6. MOJO Bluetooth Vertical Mouse with adjustable sensitivity:
The perfect grip in this Bluetooth mouse is designed to limit stress and discomfort when using a mouse for long hours. You will not face discomfort in your hands, elbows, wrist, forearms, and shoulders. This is because this MOJO wireless mouse maintains a neutral handshake grip. There is support for dual modes i.e. Bluetooth or 2.4 GHz wireless mode. You can easily control two computers simultaneously.
There is the inclusion of 6 quiet buttons. The built-in AA batteries come with a low battery indicator. When it comes to compatibility, it can work flawlessly with Android, Windows, Mac, and iOS.
Pros:
- Easy to switch modes using the button
- Compatible with different operating systems
- The easy web browsing experience
Why We Liked Vertical Mouses?
It fits perfectly in your hand for daily use at home or office. So, the users can easily switch from one mode to another with a simple push of a button.
5. Jelly Comb Advanced Vertical Wireless Bluetooth Mouses:
The ergonomic design of this Jelly Comb wireless mouse places your hand in a relaxed handshake position. Your hands attain maximum support to benefit from lasting comfort. The concave shape of the thumb and slightly extended bottom edge helps for the pinky finger. Moreover, it offers smooth movement and a comfortable grip. There is effectively a reduction in wrist strain and ache.
It is quite easy to switch between two devices through USB and Bluetooth connection. The quiet click and adjustable DPI are the two characteristics of this advanced wireless mouse. So, the silent clicks convey enhanced user experience.
Pros:
- Whisper quiet clicks
- Wide compatibility with different devices
- Offers maximum hand support for lasting comfort
Why We Liked It?
The 3 variable DPI levels enable you to alter the cursor sensitivity according to your activity. So, this Bluetooth mouse can work on various surfaces.
4. LEKVEY Rechargeable 2.4GHz Optical Vertical Mice:
This rechargeable vertical mouse is famous for its ergonomic and sleek design. This unique design benefits you with a relaxed handshake in wrist and arm positions. As a result, you get smooth movement and reduction in strain. The built-in rechargeable battery makes sure there is no need to purchase batteries. There is the presence of a nano USB receiver at the base of the mouse.
The browsing buttons offer convenience and ease of multitasking. So, the DPI levels can be adjusted in 3 settings.
Pros:
- Sleek and ergonomic design
- No need to replace batteries frequently
- Easy plug & play operation
Why We Liked Vertical Mouses?
It comes with easy plug and play operation. This LEKVEY mouse is designed for increased comfort and functionality.
3. Evoluent VM4R Vertical Mouses 4 Right Hand Ergonomic Mouse:
The VM4RW right-hand ergonomic mouse supports your right hand in an erect relaxed position. Its unique shape avoids twisting your hands against the forearm. There are no problems when programming your mouse according to your needs. The installation process is easy and quick.
There is the flexibility to alter the mouse speed. The built-in optical sensor controls are accessible on the side. So, you can use this device with all computers supporting Windows, Mac, and Linux OS.
Pros:
- Easy to adjust the mouse speed
- Thumb is comfortable to use
- Compatible with Windows, Mac, and Linux systems
Why We Liked It?
We liked its flawless supports for the right hand in an erect neutral position. So, no need to release the grip when adjusting speed.
2. J-Tech Digital Scroll Endurance Wireless Vertical Mouses:
This J-Tech wireless mouse comes in a unique ergonomic design and a removable palm rest. This palm rest reduces pain in hand and wrist. Two thumb buttons are available. They can be used for forward or reverse browser navigation. The included optical sensor comes with high resolution. Moreover, it comes with adjustable sensitivity for precision and responsiveness.
Pros:
- Keeps hands in a comfortable position
- Suitable for casual/mild gaming
- Implemented with power-saving features
Why We Liked It?
The wireless feature works well and ergonomic design is extraordinary. It is easy to operate and easy to use.
1. Anker 2.4G Wireless Vertical Ergonomic Optical Mouses:
The precise ergonomic design of this optical mouse facilitates relaxed handshake positions for wrist and arm. These positions provide smoother movement and responsiveness. The advanced tracking technology boosts sensitivity. So, this makes sure the tracking process is precise on a wide range of surfaces.
All the 5 buttons offer enhanced control on your computer systems. The previous/next buttons offer simplicity when browsing a webpage. These buttons are beneficial to gamers and working professionals. When stayed idle for 8 minutes, this mouse enters power-saving mode. So, you can press the left/right button to awake it.
Pros:
- Smooth movement and reduced strain
- Five buttons are easy to use
- Lightweight design
Why We Liked Vertical Mouses?
The grips and thumb rest perfectly fit the contour of your palm. So, throughout the use, you feel maximum comfort.
Key features to consider for the best vertical mice:
Simplify your buying decision regarding the best vertical mice. The following section highlights the key features of the same:
Weight:
The weight of a product is usually the inferior aspect but when it comes to vertical mice, it is very important to consider this aspect. A heavy mouse will be difficult to drag and difficult to carry around, particularly when you are traveling. Before making a purchase, always check the weight to avoid hassles later on. A heavier vertical mouse will be difficult to hold and move. Moreover, it feels fatigued in your hands and arms.
Buttons:
The buttons are the key components of any mouse. Generally, all mice include two buttons – left and right button. However, the vertical mice come with some extra buttons that can be useful for boosting productivity. The more the buttons, the more tasks you can perform. Also, it makes sure you rely less on the keys on the keyboard.
Certain vertical mice come with extra buttons allowing the users to assign to those buttons for particular tasks. It ultimately helps you to make a shortcut for such tasks.
Switch:
When it comes to choosing a vertical mouse, the switch we talk about is not a normal switch but a DPI switch. The DPI stands for dots per inch of the mouse that displays on the screen. Make sure your chosen vertical mouse comes with a DPI switch allowing you to adjust the DPI physically in absence of using any software. For gaming, it is better to choose a vertical mouse with high DPI so that the mouse offers more responsiveness. It becomes easy to adjust the DPI sensitivity handily.
Wired/Wireless:
Some vertical mice come with cable whereas some come without cable. It relies on personal preference and the requirement of your work. Certain people are comfortable with the use of a wired vertical mouse. This is because they dislike the hassles of charging or substituting the batteries.
For professional gamers and graphic designers, a wireless vertical mouse is a more convenient choice. This is because the wireless operation offers portability and flexibility to move the mouse. Assess the pros and cons of wired and wireless vertical mouse and accordingly choose the one based on your needs.
Concluding Note:
Whether dropping and dragging, these vertical mice work flawlessly for gaming, designing, and other professional work. They present a cost-effective solution for fulfilling multiple computing needs. They are sufficiently large to fit perfectly in hands.
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